{"id":13271,"date":"1996-01-15T15:33:00","date_gmt":"1996-01-15T23:33:00","guid":{"rendered":"https:\/\/library.consciencelaws.org\/?p=13271"},"modified":"2023-01-28T17:11:22","modified_gmt":"2023-01-29T01:11:22","slug":"abortion-induced-with-methotrexate-and-misoprostol","status":"publish","type":"post","link":"https:\/\/library.consciencelaws.org\/?p=13271","title":{"rendered":"Abortion induced with methotrexate and misoprostol"},"content":{"rendered":"\n<h4 class=\"wp-block-heading\">Ellen R Wiebe<\/h4>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"alignleft size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"171\" height=\"230\" src=\"https:\/\/library.consciencelaws.org\/wp-content\/uploads\/2019\/11\/cmaj.jpg\" alt=\"Canadian Medical Association Journal, CMAJ\" class=\"wp-image-11269\"\/><figcaption class=\"wp-element-caption\">Canadian Medical Association Journal<\/figcaption><\/figure>\n<\/div>\n\n\n<p><strong>Abstract<br>Objective:<\/strong> To determine the outcome and side effects of a new drug protocol to induce abortion. <\/p>\n\n\n\n<p><strong>Design:<\/strong> Case series. <\/p>\n\n\n\n<p><strong>Setting:<\/strong> An urban primary care practice. <\/p>\n\n\n\n<p><strong>Patients: <\/strong>One hundred consecutive patients who requested elective termination of pregnancies of less than 8 weeks&#8217; gestation. <\/p>\n\n\n\n<p><strong>Intervention:<\/strong> Subjects received methotrexate (50 mg\/m2 body surface area, administered intramuscularly) and, 3 days afterward, misoprostol (800 pg, given vaginally). <\/p>\n\n\n\n<p><strong>Outcome measures: <\/strong>Number of abortions induced within 24 hours and within 10 days of misoprostol administration, number of surgical aspirations conducted because of incomplete abortion, mean amount of bleeding and pain and the number of women who, if faced with the same situation, said they would again choose a drug-induced abortion over a surgical one. <\/p>\n\n\n\n<p><strong>Results: <\/strong>Abortion occurred within 24 hours of misoprostol administration among 48 women and within 10 days among 69 women. In total, 89 women had an abortion without surgical aspiration. Of these women, 71 said they would choose a drug-induced abortion if faced with the choice again.<\/p>\n\n\n\n<p> <strong>Conclusion: <\/strong>Abortion induced with methotrexate and misoprostol appears to be a feasible alternative to surgical abortion and deserves further study.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p>Wiebe ER. <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC1488147\/pdf\/cmaj00086-0039.pdf\">Abortion induced with methotrexate and misoprostol. <\/a>Can Med Assoc J. 1996 Jan 15;154(2):159-164. <\/p>\n","protected":false},"excerpt":{"rendered":"<p>Ellen R Wiebe AbstractObjective: To determine the outcome and side effects of a new drug protocol to induce abortion. Design: Case series. Setting: An urban primary care practice. Patients: One hundred consecutive patients who requested elective termination of pregnancies of less than 8 weeks&#8217; gestation. Intervention: Subjects received methotrexate (50 mg\/m2 body surface area, administered &hellip; <a href=\"https:\/\/library.consciencelaws.org\/?p=13271\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Abortion induced with methotrexate and misoprostol&#8221;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,2],"tags":[1652],"post_folder":[],"class_list":["post-13271","post","type-post","status-publish","format-standard","hentry","category-abortion","category-journal-article","tag-ellen-r-wiebe"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\r\n<title>Abortion induced with methotrexate and misoprostol - Protection of Conscience Project Library<\/title>\r\n<meta name=\"description\" content=\"Abortion induced with 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